TYKERB® (lapatinib) is designed to inhibit HER2 receptors
TYKERB works inside cancer cells to block HER2 receptors
TYKERB is an oral medicine
When taking TYKERB with Xeloda:
Take time to learn about TYKERB
Talk to your doctor about side effects
It is important to know that you may experience side effects while taking TYKERB.
Patient Assistance Now Oncology (PANO)
Novartis Oncology is committed to helping patients living with cancer receive the medicines they need. PANO offers quick and easy access to information about our wide range of resources.
You can get information about our PANO support program by calling 1-800-282-7630 to speak with a member of our knowledgeable staff, which is dedicated to making access to therapy as simple and convenient as possible.
IMPORTANT SAFETY INFORMATION
Do not take TYKERB if you are allergic to any of the ingredients in TYKERB.
It is not known if TYKERB is safe and effective in children.
Before taking TYKERB, tell your doctor if you have heart problems. Some people may develop heart problems while taking TYKERB, including decreased pumping of blood from the heart and an abnormal heartbeat. Call your doctor right away if you feel like your heart is pounding or racing; if you are dizzy, tired, or light-headed; or if you are short of breath. Your doctor should check your heart before and during treatment with TYKERB.
Diarrhea is common with TYKERB and may sometimes be severe. Severe diarrhea can cause loss of fluid (dehydration) and some deaths have happened. Call your doctor right away if you have a change in bowel pattern or if you have severe diarrhea. Follow your doctor’s instructions for what to do to help prevent or treat diarrhea.
If you have a cough that will not go away or are short of breath, talk with your doctor. These may be signs of lung problems.
TYKERB may cause severe skin reactions. Tell your doctor right away if you develop a skin rash, blisters, or peeling of the skin. As severe skin reactions can be life-threatening, your doctor may tell you to stop taking TYKERB.
Tell your doctor right away if you are or plan to become pregnant. You should not become pregnant when taking TYKERB because the unborn baby can be harmed. Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if TYKERB passes into breast milk. You and your doctor should decide if you will take TYKERB or breastfeed. You should not do both.
When TYKERB is taken with Xeloda, common side effects include diarrhea; red, painful hands and feet; nausea; rash; vomiting; tiredness or weakness; mouth sores; indigestion; dry skin; and nail disorders such as nail bed changes, nail pain, infection, and swelling of the cuticles.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not eat or drink grapefruit products while taking TYKERB.